Israel Vlodavsky Selected Research

Proteins (Proteins, Gene)

5/2024	Dual T cell receptor/chimeric antigen receptor engineered NK-92 cells targeting the HPV16 E6 oncoprotein and the tumor-associated antigen L1CAM exhibit enhanced cytotoxicity and specificity against tumor cells.
4/2021	In vivo modulation of ubiquitin chains by N-methylated non-proteinogenic cyclic peptides.
1/2020	Elucidating the Consequences of Heparan Sulfate Binding by Heparanase 2.
1/2017	Heparanase Overexpression Induces Glucagon Resistance and Protects Animals From Chemically Induced Diabetes.
2/2015	Overexpression of heparanase lowers the amyloid burden in amyloid-β precursor protein transgenic mice.
6/2014	Endothelial cells respond to hyperglycemia by increasing the LPL transporter GPIHBP1.
2/2012	Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer.
12/2011	Heparanase is highly expressed and regulates proliferation in GH-secreting pituitary tumor cells.
10/2008	The molecular and cellular basis of exostosis formation in hereditary multiple exostoses.
1/2008	Low and high affinity receptors mediate cellular uptake of heparanase.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Israel Vlodavsky Research Topics

Disease

178	Neoplasms (Cancer) 05/2024 - 01/2002
115	Neoplasm Metastasis (Metastasis) 03/2024 - 04/2002
66	Inflammation (Inflammations) 05/2024 - 09/2002
30	Carcinoma (Carcinomatosis) 01/2024 - 06/2006
25	Breast Neoplasms (Breast Cancer) 03/2024 - 12/2003
19	Carcinogenesis 02/2024 - 12/2003
10	Melanoma (Melanoma, Malignant) 01/2020 - 08/2004
9	Lymphoma (Lymphomas) 01/2019 - 07/2002
8	Sarcoma (Soft Tissue Sarcoma) 01/2024 - 09/2011
8	Fibrosis (Cirrhosis) 01/2022 - 05/2004
8	Glioma (Gliomas) 01/2019 - 10/2003
7	Alzheimer Disease (Alzheimer's Disease) 10/2021 - 05/2005
7	Hyperglycemia 01/2018 - 11/2002
6	Hematologic Neoplasms (Hematological Malignancy) 01/2024 - 12/2009
6	Pathologic Processes 12/2021 - 06/2003
6	Infections 12/2021 - 04/2004
6	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2021 - 03/2010
6	Diabetic Nephropathies (Diabetic Nephropathy) 06/2021 - 11/2002
6	Leukemia 06/2018 - 01/2002
5	Type 2 Diabetes Mellitus (MODY) 01/2022 - 05/2005
5	Colitis 06/2021 - 01/2007
5	Atherosclerosis 06/2013 - 01/2004
4	Virus Diseases (Viral Diseases) 12/2021 - 12/2020
4	Head and Neck Neoplasms (Head and Neck Cancer) 01/2021 - 12/2006
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 08/2004
4	Disease Progression 11/2020 - 02/2015
4	Brain Neoplasms (Brain Tumor) 01/2017 - 09/2004
4	Hypoxia (Hypoxemia) 01/2016 - 10/2005
3	Neuroinflammatory Diseases 02/2024 - 10/2012
3	Adenocarcinoma 01/2023 - 02/2007
3	Multiple Myeloma 01/2023 - 03/2011
3	Obesity 12/2022 - 01/2012
3	Stomach Neoplasms (Stomach Cancer) 08/2022 - 01/2021
3	Pancreatitis 06/2021 - 01/2017
3	Colonic Neoplasms (Colon Cancer) 01/2020 - 10/2004
3	Malignant Mesothelioma 12/2018 - 01/2004
3	Albuminuria 04/2016 - 01/2012
3	Proteinuria 04/2016 - 01/2012
3	Diabetes Mellitus 01/2016 - 05/2013
3	Vascular System Injuries 06/2013 - 01/2002
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 08/2012 - 01/2007
3	Choriocarcinoma 05/2010 - 10/2003
3	Hyperplasia 05/2008 - 01/2002
2	Urofacial syndrome 05/2024 - 01/2020
2	Glomerulonephritis 10/2022 - 04/2016

Drug/Important Bio-Agent (IBA)

220	heparanaseIBA 05/2024 - 01/2002
66	Heparitin Sulfate (Heparan Sulfate)IBA 07/2023 - 05/2002
44	EnzymesIBA 12/2022 - 07/2002
32	Glycoside Hydrolases (Endoglycosidases)IBA 10/2022 - 01/2004
25	Heparin (Liquaemin)FDA LinkGeneric 01/2024 - 01/2002
21	Proteins (Proteins, Gene)FDA Link 05/2024 - 01/2002
20	GlucuronidaseIBA 01/2021 - 07/2002
19	Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA 01/2022 - 11/2002
10	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2020 - 01/2004
9	CytokinesIBA 01/2021 - 07/2008
9	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 10/2018 - 02/2006
8	Proteoglycans (Proteoglycan)IBA 06/2021 - 10/2010
8	Messenger RNA (mRNA)IBA 12/2011 - 03/2002
7	Monoclonal AntibodiesIBA 02/2024 - 06/2006
7	Amyloid (Amyloid Fibrils)IBA 10/2021 - 05/2005
6	Peptides (Polypeptides)IBA 04/2021 - 08/2006
6	Syndecan-1 (Syndecan 1)IBA 12/2020 - 05/2007
5	Low-Molecular-Weight Heparin (Heparin, Low Molecular Weight)IBA 10/2022 - 01/2007
5	Small Interfering RNA (siRNA)IBA 01/2020 - 08/2004
5	Polysaccharides (Glycans)IBA 01/2019 - 05/2005
5	AnticoagulantsIBA 04/2015 - 01/2003
4	AntigensIBA 05/2024 - 08/2006
4	Estrogens (Estrogen)FDA Link 12/2022 - 12/2003
4	Estrogen ReceptorsIBA 12/2022 - 12/2003
4	Insulin (Novolin)FDA Link 01/2022 - 01/2017
4	SST 0001IBA 01/2016 - 03/2011
4	SelectinsIBA 05/2011 - 07/2007
3	CeruletideIBA 01/2023 - 01/2017
3	Paclitaxel (Taxol)FDA LinkGeneric 10/2022 - 10/2016
3	Blood Glucose (Blood Sugar)IBA 01/2022 - 02/2011
3	Neutralizing AntibodiesIBA 06/2021 - 01/2011
3	Interleukin-6 (Interleukin 6)IBA 11/2020 - 01/2017
3	OligosaccharidesIBA 01/2020 - 08/2012
3	P-SelectinIBA 01/2019 - 05/2011
3	LipopolysaccharidesIBA 01/2019 - 10/2012
3	ChemokinesIBA 01/2019 - 09/2010
3	ErbB Receptors (EGF Receptor)IBA 01/2018 - 12/2008
3	Sulfates (Sulfates, Inorganic)IBA 01/2017 - 04/2005
3	Vascular Endothelial Growth Factor CIBA 10/2016 - 12/2008
3	CollagenIBA 04/2016 - 11/2012
3	Lipoprotein Lipase (Diacylglycerol Lipase)IBA 01/2016 - 05/2013
3	Matrix Metalloproteinases (MMPs)IBA 06/2011 - 01/2009
3	Cell Adhesion MoleculesIBA 05/2011 - 06/2003
3	Thromboplastin (Tissue Factor)IBA 03/2008 - 01/2007
3	Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA 12/2007 - 01/2004
3	2-(4-hydroxyphenoxy)acetic acid-formaldehyde polymerIBA 01/2003 - 01/2002
2	Neural Cell Adhesion Molecule L1 (L1 Cell Adhesion Molecule)IBA 05/2024 - 01/2019
2	Chimeric Antigen ReceptorsIBA 05/2024 - 02/2024
2	CateninsIBA 02/2024 - 01/2020
2	CarcinogensIBA 01/2023 - 01/2017
2	Hormones (Hormone)IBA 12/2022 - 10/2019

Therapy/Procedure

32	Therapeutics 05/2024 - 04/2005
9	Drug Therapy (Chemotherapy) 01/2020 - 04/2005
3	Transplantation 01/2021 - 03/2008
2	Precision Medicine 03/2024 - 01/2018